Medical microneedling is one of the most popular skin treatments among patients.1 Also known as collagen induction therapy or percutaneous collagen induction, it is a medical-grade cosmetic procedure that involves using micro needles to create controlled injuries in the skin, preserving the epidermal layer.1 These micro-injuries trigger cascades of reactions to the body’s natural wound healing response, and promotes the production of collagen and elastin whilst remodelling and smoothing the skin. It is also used for transdermal drug delivery.1,2
Microneedling results in the wound healing in the dermis to be triggered, and multiple growth factors released.3 These include fibroblast growth factor, platelet-derived growth factor and transforming growth factors TGF-a and TGF-b, leading to the proliferation and migration of fibroblasts and laying down the intracellular matrix, causing…
