A recent in-vitro study has revealed that pomegranate fruit extract Pomanox may reduce signs of skin ageing.
The study conducted by EURECAT and published in the International Journal of Food Sciences has shown that the fruit extract may reduce signs of hyperpigmentation, skin dryness and loss of elasticity, by reducing melanogenesis and oxidative stress whilst modulating collagen and hyaluronic acid (HA) metabolism.
Multiple assays evaluated the effects of various concentrations of Pomanox on human fibroblast Hs68 cells under normal and UV-induced photoageing conditions. The inhibitory effects of Pomanox on tyrosinase activity were also investigated.
Analysis showed that under normal conditions, Pomanox increased collagen and HA metabolism. In cells exposed to UV, both preventative and regenerative treatments with Pomanox positively influenced HA metabolism and decreased reactive oxygen species levels.
Pomanox also showed a significant inhibitory effect on tyrosinase activity, thus potentially reducing hyperpigmentation by decreasing melanin synthesis.