Title: Fractional Microneedle Radiofrequency with the Application of Vitamin C, E, and Ferulic Acid Serum for Neck Skin Rejuvenation: A Prospective, Double-blinded, Split-neck, Placebo-controlled Trial
Authors: Jemin Kim, et al.
Published: The Journal of Dermatological Treatment, June 2025
Keywords: Ageing, Microneedling, Radiofrequency
This study aims to evaluate the efficacy of fractional microneedle radiofrequency (FMR) combined with topical antioxidant serum (vitamin C, vitamin E and ferulic acid) compared to FMR alone for neck rejuvenation. This prospective, randomised, double-blind, split-neck trial included 31 participants aged 30-65 years with visible signs of neck ageing. Subjects underwent two FMR treatments at four-week intervals. Immediately post-treatment, participants applied antioxidant serum to one randomly assigned side of the neck and placebo to the contralateral side…
