Dr Beata Cybulska explores the use of nutraceuticals for increasing collagen and hyaluronic acid production
Ageing is a complex process caused by genetic, hormonal and environmental factors, affecting all the cells and organs of the human body.1-4 Most of the signs of ageing in connective tissues are associated with dysregulation of the collagen matrix, rise in inflammatory markers and reduced blood flow. It is produced by fibroblasts alongside elastin and keratin fibres, which provide integrity and firmness to the tissues. Degradation of the collagen matrix with age impacts on the activity of fibroblasts, resulting infewer collagen fibres being produced, diminished hydration and supply of oxygen and nutrients, resulting in impaired immune responses. Ultraviolet irradiation induced matrix metalloproteinases in the epidermis and dermis result in degradation of collagen and are regarded as primary mediators of connective tissue ageing.5 Skin, being the largest and most visible connective tissue…
