Hyaluronic acid (HA) injectable fillers are the most widely used dermal fillers to treat facial volume deficits.1 Appreciating the physico-chemical properties of dermal fillers is crucial for making well-informed choices in product selection.
HA fillers exhibit different characteristics depending on their manufacturing process technologies, which are designed to fine-tune the mechanical properties to achieve desired biological outcomes post injection.1 Once augmented, fillers undergo both shear stress and vertical compression/elongation forces, leading to the deformation of the filler.1
In states of low stress, dermal fillers manifest gel-like properties. However, as shear stress increases, they exhibit varying degrees of flow, influenced by the specific manufacturing conditions and composition.1 Understanding these dynamic properties is instrumental in the optimisation of dermal filler…