Considering Regenerative Approaches for Ageing Hands

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Consultant hand surgeon and aesthetic practitioner Mr Lorenzo Garagnani shares his protocol for restoring hydration and elasticity in ageing hands

Ageing hands are among the most visible indicators of age and yet can be frequently overlooked in facial-focused aesthetic practice.1 This is largely due to limited practitioner familiarity with hand anatomy and aesthetic indications, as well as low patient awareness of available treatment options.
Frequently, patients report dissatisfaction with changes in the hands such as skin thinning, crepiness, volume loss, fine lines and dehydration.2 These changes are largely driven by a combination of environmental damage – such as sun damage, contact with harsh chemicals and exposure to extreme climate – and by ageing and hormonal changes leading to reduced collagen production, impaired skin barrier function, dermal thinning and elasticity loss.3,4
With the growing preference for more natural, regenerative approaches, polynucleotides (PNs) offer a promising solution for hand rejuvenation. This article explores the anatomical considerations…

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