Dr Mario Luca Russo and Dr Marcello Poltronieri review microneedling with exosome solutions for skin regeneration
Antiageing, inhibiting hyperpigmentation and preventing hair loss are among patient demands in medical aesthetics. Exosomes are nanovesicles secreted by cells that play an important role in intercellular communication.
Compared to drugs, plant and herbal extracts and bioactive molecules, exosomes have the advantage of low immunogenicity, good biocompatibility, targeting specificity and strong tissue permeability.1 This article explores how microneedling with exosome solutions enhances skin regeneration and addresses key aesthetic concerns.
Exosome origins
The collection and purification of exosomes are complex because exosomes from different sources vary in size, composition and function. One of the current challenges is efficiently enriching exosomes, which is vital for their engineering and production.2,3 Bovine milk-derived exosomes are isolated from fresh bovine milk, with diameters…
