Skeletal muscle is a dynamic, metabolically active organ essential for maintaining health throughout the lifespan. Beyond providing strength and locomotion, muscle regulates glucose metabolism, supports immune signalling and contributes to endocrine communication through the secretion of myokines.1 A decline in muscle mass and function, known as sarcopenia, represents one of the most clinically significant hallmarks of ageing and is associated with frailty, metabolic dysfunction, reduced mobility and diminished quality of life.2
In modern clinical practice, muscle health must be reframed as a therapeutic priority rather than an incidental outcome of exercise. The rapid adoption of pharmacological weight-loss therapies, particularly glucagon-like peptide-1 (GLP-1) receptor agonists, has intensified the importance of preserving lean tissue.2 While these medications provide unprecedented…
