Numerous studies have endorsed the incorporation of hydroxy acids, such as glycolic and mandelic acid, in formulations for antiageing skincare and cosmeceuticals.1-33 Despite the presence of first-generation hydroxy acids since 1974, the recent surge in popularity is attributed to new hydroxy acids offering additional benefits that contribute to the enhancement of skin barrier function. The four new primary types of hydroxy acids encompass polyhydroxy acids (PHAs), beta hydroxy acids (BHAs), aldobionic acids (BAs), and aromatic hydroxy acids (AMAs).1
With reference to alpha hydroxy acids (AHAs) like glycolic acid, lactic acid, citric acid, and mandelic acid, there exists a wealth of literature supporting their widespread application in antiageing cosmeceutical formulations. Notably, AHAs are recognised for their role in enhancing the keratinocyte maturation process and promoting cell…