Profhilo® Haenkenium® is a unique and innovative topical formulation which deeply nourishes the skin at a cellular level. This advanced hyaluronic acid complex utilises a patented botanical extract of Salvia Haenkei (0.25%), also known as Prawn Sage, which originates from Bolivia with proven anti-ageing properties. An integrated senescence-screening assay conducted by Matic et al., (2016) outlines findings from more than 3,000 chemical and natural compounds to demonstrate that Salvia Haenkei decreased replicative and UV-mediated senescence in human primary fibroblasts, as well as in a model of in vitro reconstructed human epidermis. Furthermore, the authors report pre-clinical and clinical testing of this extract by performing toxicity and irritability evaluation in vitro to demonstrate the safety of Salvia Haenkei extract for use as a safe and effective anti-ageing skin treatment.
In addition, phosphatase and tensin homolog protein (PTEN) is a key cellular senescent regulator (Childs et al., 2015), and data from Matic et al., (2016) demonstrate that Salvia Haenkei is a strong…
