It is commonly recognised that vitamin C affects a wide variety of skin functions; therefore, it is essential to include when building skincare routines for our patients. Topical application of vitamin C to the skin can have a significant impact on skin rejuvenation, but understanding its many complexities is of upmost importance for successful results.
The most abundant antioxidant in human skin, vitamin C,1 is a natural skin constituent and found at high levels in both the epidermis and dermis.2,3 L-ascorbic acid is the most biologically active and well-studied form of vitamin C, so will be discussed in this article.4
Arguably, the most relevant free radical to ageing is ultraviolet radiation (UVR).5,6 UV-induced erythema and thymine dimer mutations (DNA mutations caused by UV radiation) that contribute to skin cancer are reduced by sunscreen.7 However, research has suggested that…
