Three practitioners discuss protocols for topical peptides within clinical management
Topical peptides have been gaining momentum in evidence-led skincare, valued for their ability to support skin repair and address visible signs of ageing through targeted biological signalling.¹⁻⁴ Unlike traditional active ingredients that primarily exfoliate or protect the skin, peptides act as cell-signalling molecules capable of influencing processes involved in collagen synthesis, barrier function and inflammation.¹⁻⁵ While their clinical effects depend on peptide structure, formulation and skin penetration, growing evidence suggests that selected topical peptides can improve skin firmness, fine lines, hydration and overall skin quality.⁶⁻¹⁰
Topical peptide formulations encompass several functional classes, including signal peptides, carrier peptides, enzyme-inhibiting peptides and neurotransmitter-inhibiting peptides, each designed to target different aspects of skin ageing and…
