A summary of the latest clinical studies
Title: A Comprehensive Evaluation of Patient Satisfaction and Clinical Outcomes in Poly-L-Lactic Acid Treatments-A Randomized, Interventional, and Comparative Clinical Study
Authors: Victor R M Munoz-Lora, et al.
Published: Journal of Cosmetic Dermatology, May 2026
Keywords: Facial anatomy, Poly-L-lactic-acid, Ultrasound
To evaluate the impact of PLLA formulation and injection depth (subcutaneous vs. supraperiosteal) using objective and subjective assessments, this randomised clinical study with split-face and parallel components included 20 participants. Each participant received a single PLLA formulation of PLLA-SCA (Sculptra) or PLLA-ELL (Elleva), while the injection plane was alternated between hemifaces. Dermal thickness was assessed using ultrasonography at baseline, 60, and 120 days. Patient satisfaction was evaluated using the Global Aesthetic Improvement Scale (GAIS). Dermal…