Dr Paul Charlson outlines a comprehensive review of biostimulators
A biostimulator is defined as an injectable substance that stimulates the body’s natural regenerative processes, by encouraging collagen production.¹ The global bioregenerative injectable market is projected to grow from £1. 20 billion in 2025 to £2. 83 billion by 2033, with biostimulatory injectables representing the largest segment of this growth. This is due to their ability to promote tissue regeneration and improve skin quality, rather than simply providing immediate volumisation.² This article focuses specifically on injectable biostimulator products within this category, including polylactic acid (PLA), calcium hydroxyapatite (CaHA), poly-ε-caprolactone (PCL) and hybrid biostimulators.
Exploring the context
The use of biostimulators in aesthetics dates back to the late 1990s, when poly-L-lactic acid (PLLA) was first used to treat lipodystrophy in patients with Human Immunodeficiency Virus.³–⁵ CaHA and…
