Fat is a ubiquitous component of the subcutaneous tissues. We used to think of fat as the equivalent to a ‘savings account’ of nutrients when metabolic expenditure exceeds caloric intake.1 However, as our understanding of the dynamics of ageing evolves, a complex interplay in multiple tissue layers is emerging.
Adipose tissue and the age-related changes in its distribution throughout the body has attracted enormous attention over the last decade as it is now a known fact that fat distribution patterns affect the appearance of our body as we age.2-4 Treating increased focal adiposities or selective loss of fat as seen in lipoatrophy has become a large component of cosmetic surgery and aesthetic medicine. Numerous surgical techniques and non-invasive technologies exist that can successfully improve either focal accumulation of fat or volume loss and shift. For instance, facial volume loss…