Considerations for HA Dissolution

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As aesthetic practitioners are aware, hyaluronidase is an important drug that is commonly used off-label to dissolve hyaluronic acid (HA) dermal filler.1-3 Whether it be for the correction of an unaesthetic result, or, in more serious and time-sensitive situations, the resolution of a major complication such as a vascular occlusion, hyaluronidase is the only way we are able to remove a hyaluronic acid (HA) dermal filler without causing damage to the skin’s surface.1,4 When it comes to hyaluronidase dosing, there are guidelines available for practitioners to refer to that outline its use for different anatomical areas,1 and dosing is often outlined in published papers.5-7
The Aesthetics Complications Expert (ACE) Group guidelines which, to my knowledge, are what most practitioners in the UK use, state that hyaluronidase dosage depends on several factors according to the individual…

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