Mesotherapy was developed in 1952 by Dr Michel Pistor who described it succinctly as, ‘A little volume, a few times and in the right place’.1 Today, it is a well-established treatment in which liquid or gel compounds are injected intradermally at various depths, at multiple injection sites, to trigger or support aesthetically corrective processes in the skin, through a combination of physical stimulation, pharmacological effect, and appropriate microdosing.1
Although there are many indications – such as cellulite, stretch marks and alopecia – this article will focus on the core ingredients supporting skin rejuvenation. Various injection techniques and devices are used, from manual injection and nappage, to sophisticated devices, which deliver grid dosage of the required substrates, but they are outside the remit of this article.1-3
Mesotherapy is often used synergistically with other protocols, including topical application regimes, intra-dermal treatments such as carboxytherapy (which improves microcirculation and…
