Combining Topical Regenerative Therapy with Microneedling

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Independent nurse prescriber Nina Prisk demonstrates skin recovery and patient outcomes following microneedling with adjunctive topical therapy

Microneedling is a well-established regenerative procedure that improves skin quality through controlled dermal injury, stimulating collagen synthesis, elastin remodelling and extracellular matrix (ECM) renewal.¹⁻⁴ Although its efficacy is well supported, the acute inflammatory response associated with treatment frequently results in transient erythema, oedema and discomfort, which may influence patient satisfaction and adherence to treatment programmes.⁵˒⁶ Growing interest has focused on topical regenerative therapies designed to complement physiological wound healing during the immediate post-procedure period. Topical ingredients, including polydeoxyribonucleotide (PDRN), exosome-derived technologies, biomimetic peptides, and low molecular-weight hyaluronic acid (HA), have been investigated for their potential to support barrier recovery, cellular signalling and tissue…

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