Hyaluronic acid (HA) is a widely used biocompatible component in aesthetic injectables due to its safety and efficacy. It is one of the main components of the extracellular matrix and ground substance and is therefore indispensable for the cellular framework.1
HA is capable of hydration, lubrication and returning of elasticity to the skin, maintaining the shape of tissues and strengthening tissue tone.2 The greatest amount of HA is present in the skin and comprises around half of the body’s total volume of HA.3
This article will focus on HA as the main component for skin biorevitalisation and hydration in areas of the face, neck, décolletage and dorsum of the hands using mesotherapy techniques.
The majority of HA used in skin hydration and biorevitalisation is non-cross-linked. As the product is injected into the dermoepidermal junction, it aids to add HA to the layers undergoing mitotic…