Practitioners consider collagen biostimulating injectables and their expanding role in skin rejuvenation
Biostimulating injectables are advanced aesthetic agents, designed to enhance facial rejuvenation by stimulating the skin’s intrinsic regenerative processes, particularly collagen, elastin and extracellular matrix (ECM) production.1 Unlike hyaluronic acid (HA) dermal fillers that provide immediate volumisation, collagen biostimulants promote progressive, biologically driven improvements in skin density, texture, hydration and elasticity.2,3
Common collagen biostimulating materials, such as poly-L-lactic acid (PLLA), calcium hydroxylapatite (CaHA) and polycaprolactone (PCL), stimulate fibroblast activity and promote dermal remodelling, resulting in natural-appearing rejuvenation outcomes.4 While all biostimulants promote tissue regeneration, their mechanisms differ; polynucleotides (PNs) and platelet-rich plasma (PRP) provide growth factors and nucleotides to support cellular repair…
